Natural preparations for the treatment of insomnia and anxiety: 

Insomnia:

Melatonin is a serotonin derivative produced mainly in the pineal gland. It regulates sleep-wake cycles. Melatonin improves sleep onset, duration and quality of sleep. Melatonin levels naturally rise at night and they decrease in the mornings. It is used extensively for treatment of insomnia. Ramelteon and Tasimelteon are agonists for melatonin receptors. 

Valerian root, is a herb found in Asia and Europe. It is used to aid insomnia. 

Magnesium, is also used to induce sleep and treat insomnia. Magnesium increases the levels of GABA in the brain thus producing a calming effect. It also regulates the production of melatonin, thus serving as a sleep aid to patients struggling with insomnia. 

Glycine is an amino acid in the CNS that also improves sleep. Glycine is believed to lower body temperature at night signaling to the body it is time to sleep. Glycine helps you to fall asleep faster and it improves the quality of your sleep. 

Anxiety:

Chamomile is a herb used to reduce anxiety. Its anxiolytic properties can be attributed to the flavonoid apigenin, which increases GABA in the brain. 

Ginkgo is prepared from the leaves of Ginkgo biloba, and contains glycosides and terpenoids.  Ginkgo is used as a herbal anxiolytic. It possesses antioxidant effects and increases nitric oxide formation. 

St. John's Wort is made from dried flowers of Hypericum perforatum, which contains the active constituents hypericin and hyperforin. This produces a decreased activity of serotonergic reuptake systems. It is used to treat anxiety as well as mild to moderate depression. 

Sources

Petre, A. (7 August 2020). 9 Natural Sleep Aids. Available: https://www.healthline.com/nutrition/sleep-aids#_noHeaderPrefixedContent. Last accessed 3 March 2021.

Bertram G. Katzung. (2015). Dietry Supplements and Herbal Medication. In: Anthony J. Trevor Katzung & Trevor's Pharmacology Examination & Board Review . 11th ed. United States of America: Mc Graw-Hill Education. 492-495.