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29 Apr 2021, 14:56 Publicly Viewable

system:	effects:
CNS	decrease blood flow within the brain may cause vasodilation which increases cerebral blood flow and intracranial pressure
CVS	Volatile drugs decrease mean arterial pressure either via myocardial depression or vasodilation decreasing of preload and afterload can take place a dose-dependent decrease in arterial blood pressure drugs can also depress normal cardiac contractility
renal	there is a decrease in GFR and urine flow and can also cause decreased renal blood flow
hepatic	decrease in portal vein blood flow persistent elevation in liver enzymes especially in Halothane
uterus	potent uterine relaxant can also increase uterine bleeding after delivery of the baby
respiratory	bronchodilation airway irritation decrease in tidal volume and an increase in respiratory rate all volatile drugs are respiratory depressants

Major acute toxicities of inhalation anesthetics :