Botanical substances or natural substances are plant based medicines that don't have to go through the rigorous testing that registered medicines do. These substances are therefore dangerous to use without the input of a pharmacist or a doctor as they can still have adverse effects on a patient as well as have a contra-indication or a bad interaction with medicines that are already being used by the patient. These medicines might be considered 'safer' due to the fact that it is a natural product but it is more dangerous because of the information we do not have. 

Botanical substances for use as anxiolytics: Lavender, Valerian, Passion flower, Lemon balm, Linden, Chamomile. 

Botanical substances for uses as hypnotics: Passion flower, Jamaican dogwood, Skullcap, Motherwort, Hops, Californian poppy.