Name an example of each of the three phenothiazine sub-families and state how they differ from one another in terms of potency and side effects.

The 3 sub-families/derivatives include 
- Alphatic side-chain - Low potency (little extra pyrimaidal effects, severe sedation, strong anti-cholinergic effects (dry mouth constipation urine retension etc), cardiotoxic (arrythmiasis) postural hypotension) 
- Piperidine side chain (goes together with alphatic side chain effects).
- Piperazine side chain (unlinke the previous 2 side chains it has opposite effects, high potency and more extra pyramidal effects, weakerer anti cholinergic, alpha lytic , sedation and cadriovascular effects.

Which receptors in particular are blocked by the typical antipsychotic drugs?
The Typical Antipsychotic drugs are likely to block the Dopamine Receptors in the mesolymbic pathyway (D2-R) and then the D2 receptors in the Mesolymbic system

How does the mechanism of action of the atypical drugs differ from that of the typical drugs?
The Typical drugs Mainly block the Dopamine reseptors and has an affinity to dopamine receptors only. The Atypical drugs has a high affinity for 5-HT2a and 5-HT2c receptors (antagonist).

Which of the receptors blocked by the older drugs reduce the risk of extrapyramidal side effects?
The Aliphatic and Piperidine side chain drugs such as Chlorpromazine and periciazine.

Which of the older drugs have a high incidence of extrapyramidal side effects? What is the reason for this?
Butyrophenone derivatives- Haloperidal has a high prevalence of Extrapyramidal side effects. 

Because of which receptor(s) blockade do the aliphatic group of drugs have a high incidence of autonomic side effects?
Due to the blockade of the Muscarinic reseptors.