Sinusitis, allergen exposure, stimuli such as heat, smoke and cold, cold air, chemical or drug damage and physical damage.
Alfha 1-agonists- ephedrine, antihistamines- diphenhydramine, corticosteroids-prednisone, mast cell stabilisers- ketotifen, mucolytics- acetylcysteine, antibiotics- neomycin, diverse drugs- normal saline.
Decongestants can have systemic side effects if administered by another route other then topical because they are agonists for alpha 1 receptors and there duration of treatment is also longer with topical administration. They are administered topically with nasal sprays and gels.
Rhinitis medicamentosa is a condition that develops due to long term use of decongestant nasal spray that causes it to not have an effect anymore. It can be treated with cortisone nasal sprays, like beclomethasone.
The first generation is effective, but it gives sedation and lowers concentration. Second generation doesn't and can be used for long term. They should not be used to relieve cold Rhinitis, because the fast action and long term duration of the first generation is preferred.
They decrease mucus production and decrease bronchodilation in nasal Rhinitis. They are administered through nasal sprays.