Fluvoxamine has an anti-inflammatory effect and is therefore, used to help Covid patients. Fluvoxamine binds to sigma-1 receptor in the immune cells of the body, reducing the production of inflammatory cytokines.
https://www.covid19treatmentguidelines.nih.gov/therapies/immunomodulators/fluvoxamine/#:~:text=Anti%2DInflammatory%20Effect%20of%20Fluvoxamine,reduced%20production%20of%20inflammatory%20cytokines.
COVID-19 could lead to serious illness as a result of an excessive immune response. Fluvoxamine could prevent clinical deterioration by stimulating the σ-1 receptor, which regulates cytokine production.