Inhalation anaesthetic

Effects

Cardiovascular

CNS

Respiratory

Hepatic

Uterus

Halothane

Depress cardiac contractility

Sensitises myocardium to adrenaline

Ventricular arrhythmias

Increase cerebral blood flow and intracranial pressure

Bronchodilation

Causes rapid, shallow breathing

Depresses muco-ciliary function

No salivary secretions, bronchial secretions, or functions

Hepatotoxicity

Desflurane

Depress cardiac contractility

Greater vasodilation with minimum effect on cardiac output

Increase blood pressure and heart rate

Increase cerebral blood flow and intracranial pressure

Bronchodilation

Causes rapid, shallow breathing

Depresses muco-ciliary function

Muscle relaxant

Enflurane

Depress cardiac contractility

Sometimes convulsions can occur

Bronchodilation

Causes rapid, shallow breathing

Depresses muco-ciliary function

Potential nephrotoxicity

Isoflurane

Depress cardiac contractility

Greater vasodilation with minimum effect on cardiac output

Increases heart rate

Bronchodilation

Causes rapid, shallow breathing

Depresses muco-ciliary function

Sevoflurane

Depress cardiac contractility

Greater vasodilation with minimum effect on cardiac output

Increase cerebral blood flow and intracranial pressure

Bronchodilation

Causes rapid, shallow breathing

Depresses muco-ciliary function

Muscle relaxant

Nitrous oxide

Megaloblastic anaemia

Potent analgesic

Amnesia

Increases cerebral blood flow therefore increasing intracranial pressure

Depresses muco-ciliary function