1. Alcohol metabolism follows zero-order kinetics. The body will only be able to metabolize alcohol until all NAD enzymes are saturated and then the feeling of intoxication starts. 
2. Alcohol is metabolized via two pathways. 

• Alcohol dehydrogenase 
• MEOS, these enzymes convert alcohol to acetaldehyde, which is then converted to acetate through the aldehyde dehydrogenase enzyme.

3.  Drugs that influence the metabolism of acetaldehyde to acetate include disulfiram, cephalosporins, and hypoglycemics.  They inhibit aldehyde dehydrogenase and this means acetaldehyde cannot be converted to acetate.  This excessive acetaldehyde in the body causes nausea, headache, hot flushes, and fever.