LUNE HUGGETT
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Lune' Huggett 31913377 Blog #6

7 Mar 2021, 18:32 Publicly Viewable
  1. Like with most neurotransmitters, the more a receptor is stimulated, the more it takes to saturate that specific receptor. Therefore when a person consumes a lot of alcohol it can saturate the ethanol-induced up-regulation that responds to a continuous alcohol consumption.
  2. Continued alcohol consumption can have an impact on the liver due to the ethanol oxidation in the liver. The by-products caused by the metabolism of the ethanol is toxic and can cause inflammation.
  3. Wernicke-Korsakoff syndrome is caused by thiamine deficiency and can be treated with parenteral thiamine.
  4. Foetal alcohol syndrome is a disorder caused by the mother drinking constantly during her pregnancy. The alcohol travels through the placenta until the foetuses alcohol concentration is the same as the mothers. This triggers neurodegeneration and causes neuronal and glial migration. This causes mental retardation and congenital malformations.
  5. In acute alcohol consumption the enzymes involved are mostly alcohol dehydrogenase and MEOS whereas with chronic alcohol consumption, mostly MEOS are the active enzymes.
  6. Aspirin, Paracetamol, Vasodilators, Hypoglycemic drugs