Pain, a uncomfortable, sensory and emotional experience caused by actual or potential tissue damage. It can be measure on a scale from 0, no pain to 10, unbearable pain. Pain can be described as a burning, stinging , dull, sharp and aching. Nociceptors, tissue damage cells, picks up the pain stimulus and sends it to the brain via spinal-cord, this is interpreted by neurons in the grey matter of the brain, this pain signal activates the salience network. Further the motor network is stimulated to remove the source of the pain from body part where the pain is experienced. Other chemical sis also releases to help the brain and the body to cope with the pain, for example enkephalins and endorphins. These different methods to manage pain in the body is different for every person thus people experience pain different, and the management there off also differ. Mild pain is treated with over-the-counter medication to treat the cells where the pain starts. Severe pain is treated with prescribed medication where the perception of the pain is influenced, by blocking the stimulus or by increasing the excretion of endogenous peptides such as endorphins to help with the coping of the pain.