Serotonin 1D/1A - play a role in migraines by stimulating smooth muscles in the intracranial blood vessels, causing vasoconstriction and preventing vasodilation that leads to a migraine.

Ergots- they are partial agonists at alpha and serotonin receptors, they also play a role in prophylaxis and preventing acute attacks of migraine. 

Anti - inflammatory drugs can also be used for pain, associated with migraines such as ibuprofen and aspirin. 

Other drugs that can be used are, beta blockers and calcium channel blockers..