This refers to when a person experiences loss of memory of any new experience done during the drug’s use of action, drugs such as triazolam, lorazepam and midazolam may cause this.
These drugs result in hyperpolarization and thus cause an inhibitory effect on the post synaptic neurons and the internueronal transmission resulting in skeletal neuromuscular junction depression and they cause muscle relaxation.
RS: these drugs can cause the medulla respiratory center to be depressed, this depression is usually seen in patients with pulmonary disease
CVS: These drugs can cause depression of the medullary vasomotor, and is this depression is seen in patients with CVS problems and impairments which may lead to fatal problems