Piperidine derivatives: Thioridazine
Piperazine: Fluphenazine
The aliphatic and piperidine derivatives have a low potency, low EPS, high sedation, high anticholinergic and alpha-lytic effects and cardiotoxicity. The piperazine derivatives have a high potency and EPS but have low sedation, low anticholinergic and alpha-lytic effects and low cardiotoxicity.