TIHAN JOUBERT

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Blog #2

7 Mar 2021, 18:00 Publicly Viewable

Anterograde amnesia is inability to remember events occurring during the drug’s duration of action, and this can be caused by benzodiazepines.

Sedative-hypnotics decreases the time it takes to fall asleep, it increases the duration of NREM sleep while decreasing the duration of REM sleep where rapid eye movement takes place, it also decreases your deep sleep stage a.k.a your slow wave sleep.

The barbiturates thiopental and methohexital are very lipid soluble and penetrates the brain tissue rapidly following IV administration and this favors their use for induction in general anesthesia.

Benzodiazepines including clonazepam, nitrazepam, lorazepam and diazepam are sufficiently selective to be useful in the management of seizures.

Carbamates and BD exert an inhibitory effect on polysynaptic reflexes and internuncial transmission and at high dosages depresses the neuromuscular junction.

At hypnotic doses in healthy patients the effects of sedative hypnotics are comparable to changes during natural sleep, they can produce significant pulmonary depression in patients with pulmonary disease.