IV MOLEMA

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Blog 2.4

14 Oct 2021, 08:37 Publicly Viewable

1) via endothelium dependent vasodilation, increasing calcium levels leading to the release of EDRF, which releases Nitric oxide.

2) a constitutive enzyme is constantly synthesized and persist in one area. Induced enzyme, they need to be stimulated first for them to work and their effects are small.

3) nitic oxide causes vasodilation which leads to decrease in blood pressure in high doses it might lead to hypotension. Sepsis in an inflammatory response to infections, Induces INOS macrophage leading to severe hypotension and shock. 

4) nitric oxide

5) via Nos enzymes inhibition to arginine. 

6) nitric oxide is released due to tissue injury leading to inflammatory actions or via the PG synthesis via COX-2.

7) by acting as a neurotransmitter in the brain, used in the treatment of Parkinsonism and stroke.