I GROENEWALD
Blog 8
20 Mar 2021, 22:24
Compile a table, listing the major effects on every system (cardiovascular, CNS, renal, hepatic and uterus) for all the inhalation anaesthetics. This table is important when it comes to the selection of drugs in certain individuals.
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Inhalation anaesthetics |
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Drug |
Systems |
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Cardiovascular |
CNS |
Renal |
Hepatic |
Uterus |
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Nitrous Oxide |
None |
Weak anesthetic Potent analgesic amnesia
|
None |
None |
None |
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Desflurane |
Relaxant |
Induction Increase cerebral blood flow |
Muscle relaxant. |
May promote hepatotoxicity |
Decrease muscle contractions |
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Sevoflurane |
Relaxes non depolarising muscles |
Induction and maintenance |
Muscle relaxant. |
Metabolise |
Decrease muscle contractions |
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Isoflurane |
Muscle relaxant but do not sensitize myocardium |
Induction |
Muscle relaxant. |
May promote hepatotoxicity |
Decrease muscle contractions |
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Enflurane |
Muscle relaxant Does not sensitize myocardium |
Smooth muscle induction may cause convulsions |
Muscle relaxant. |
May promote hepatotoxicity. |
Decrease muscle contractions |
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Halothane |
Sensitize myocardium and decrease blood pressure |
Fast smooth muscle induction Increase cerebral blood flow |
Muscle relaxant. |
Rare hepatotoxicity. |
Decrease muscle contractions |
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Methoxy-flurane |
Muscle relaxant
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Muscle induction |
Muscle relaxant. |
May promote hepatotoxicity. |
Decrease muscle contractions |
Name the major acute toxic effects of the inhalation drugs:
- Bradycardia.
- Increase intracranial pressure.
- May cause convulsions.
- Irretention of airways.