There are two categories of hallucinogenic drugs: classic hallucinogens and dissociative drugs.
Short-term effects of hallucinogenic drugs include: dizziness and sleeplessness, impulsiveness and rapid emotional shifts, euphoria, increased blood pressure, heart rate and body temperature, loss of appetite, dry mouth and sweating, numbness, weakness and tremors. The clinical profile of a patient that used hallucinogenics always include altered mental status and agitation.
A benzodiazepine (phenobarbital and diazepam) is given to a patient that overdosed on LSD to calm them, to reduce agitation and to normalize the operation of the CNS. For convulsions anti-epileptics can be administered. Chlorpromazine can be given to eliminate the hallucinogen and to bring back the consciousness of the patient. For vomiting, and antiemetic such as metoclopramide can be given.
Physostigmine, an AChE-inhibitor is given to reverse the toxicity. A benzodiazepine can also be given.